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14462 Sigma-Aldrich

(−)-α-Bisabolol

≥93% (GC)

Synonym: (−)-6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol, (-)-alpha-Bisabolol, Levomenol

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Properties

Related Categories Acyclic, Alkenes, Building Blocks, Chemical Synthesis, Organic Building Blocks More...
assay   ≥93% (GC)
optical activity   [α]/D -58±5°, neat
refractive index   n20/D 1.496
SMILES string   C\C(C)=C\CC[C@](C)(O)[C@H]1CCC(C)=CC1
InChI   1S/C15H26O/c1-12(2)6-5-11-15(4,16)14-9-7-13(3)8-10-14/h6-7,14,16H,5,8-11H2,1-4H3/t14-,15+/m1/s1
InChI key   RGZSQWQPBWRIAQ-CABCVRRESA-N

Description

General description

(-)-α-Bisabolol is the major constituent of essential oil from leaves of Hymenocrater yazdianus.

Application

(-)-α-Bisabolol was used to investigate the leishmanicidal and cytotoxic activity of essential oil of Vanillosmopsis arborea.

Packaging

5, 25 mL in glass bottle

Biochem/physiol Actions

α-Bisabolol is active against primary acute leukemia cells, including BCR-ABL(+) acute lymphoblastic leukemias. It is the inhibitor of voltage-dependent Ca(2+) channels in tracheal smooth muscle preparations of rat. It also inhibits human and rat glioma cell growth and survival. It is a potential new therapeutic agent against leishmaniasis.

Safety & Documentation

Safety Information

Symbol 
GHS09  GHS09
Hazard statements 
Personal Protective Equipment 
RIDADR 
UN 3082 9 / PGIII
WGK Germany 
3
Flash Point(F) 
275 °F
Flash Point(C) 
135 °C

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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