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154563 Aldrich

Tris(hydroxymethyl)aminomethane

ultrapure grade, ≥99.9%

Synonym: 2-Amino-2-(hydroxymethyl)-1,3-propanediol, THAM, Tris base, Trometamol

  • CAS Number 77-86-1

  • Linear Formula NH2C(CH2OH)3

  • Molecular Weight 121.14

  •  Beilstein Registry Number 741883

  •  EC Number 201-064-4

  •  MDL number MFCD00004679

  •  PubChem Substance ID 329750892

Purchase

Properties

grade   ultrapure grade
InChI Key   LENZDBCJOHFCAS-UHFFFAOYSA-N
assay   ≥99.9%
useful pH range   7 - 9
pKa (25 °C)   8.1
bp   219-220 °C/10 mmHg(lit.)
mp   167-172 °C(lit.)

Description

Application

Buffer and primary pH standard. pKa=8.3 at 20°C. Auxiliary material in pharmaceutical science.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
TY2900000

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
What does the "ultrapure grade" in the description of Product 154563, Tris(hydroxymethyl)aminomethane, indicate?
This material has been specifically purified to have the lowest heavy metals and iron content.
What solvents can be used to dissolve Product T54563, Trometamol?
According to the Merck Index (which we also offer as Product No. Z705322), this material is expected to be soluble in water (550 mg/mL), ethylene glycol (79.1 mg/mL), methanol (26 mg/mL), anhydrous ethanol (14.6 mg/mL), 95% ethanol (22 mg/mL), dimethylformamide (14mg/mL) and acetone (2mg/mL) at room temperature.
Where can I find more technical information onProduct T54563, Trometamol, and other buffers?
Please visit the Learning Center in our Buffer Explorer section of the website. There you will find helpful formulas, buffer calculator tools and other property information on our buffer products.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
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