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263478 Sigma-Aldrich

4-Bromo-1,2-difluorobenzene

98%

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Properties

Related Categories Aryl, Aryl Fluorinated Building Blocks, Building Blocks, C6, Chemical Synthesis,
Quality Level   100
assay   98%
refractive index   n20/D 1.505 (lit.)
bp   150-151 °C (lit.)
density   1.707 g/mL at 25 °C (lit.)
SMILES string   Fc1ccc(Br)cc1F
InChI   1S/C6H3BrF2/c7-4-1-2-5(8)6(9)3-4/h1-3H
InChI key   YMQPKONILWWJQG-UHFFFAOYSA-N

Description

General description

Regioselective nucleophilic aromatic substitution reaction of 4-bromo-1,2-difluorobenzene with benzyl alcohol has been investigated.

Application

4-Bromo-1,2-difluorobenzene has been used in the preparation of 4-benzyl-2-(3,4-difluorophenyl)-2-hydroxy-morpholine.

Packaging

10 g in ampule

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
RIDADR 
UN 1993C 3 / PGIII
WGK Germany 
WGK 2
Flash Point(F) 
91.4 °F - closed cup
Flash Point(C) 
33 °C - closed cup
Protocols & Articles
Peer-Reviewed Papers
15

References

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