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37347 Sigma-Aldrich

O-(2-Oxo-1(2H)pyridyl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate

≥99.0% (HPLC)

Synonym: O-(1,2-Dihydro-2-oxo-1-pyridyl)-N,N,N′-N′-tetramethyluronium tetrafluoroborate, TPTU

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Properties

Related Categories Chemical Biology, Chemical Synthesis, Coupling, Peptide Coupling, Peptide Synthesis and Peptide Chemistry,
Quality Level   100
assay   ≥99.0% (HPLC)
application(s)   peptide synthesis: suitable
mp   140 °C (dec.) (lit.)
storage temp.   2-8°C
SMILES string   F[B-](F)(F)F.CN(C)C(\ON1C=CC=CC1=O)=[N+](/C)C
InChI   1S/C10H16N3O2.BF4/c1-11(2)10(12(3)4)15-13-8-6-5-7-9(13)14;2-1(3,4)5/h5-8H,1-4H3;/q+1;-1
InChI key   CZQGINAUZYECAI-UHFFFAOYSA-N

Description

Application

Reagent for:
Amidation
Peptide Coupling
Esterification of nucleosides to solid phase supports for oligonucleoside synthesis

Packaging

5, 25 g in glass bottle

Other Notes

Coupling reagent for peptide synthesis, especially suited for segment condensation with little racemization

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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