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410233 Sigma-Aldrich

1H-Benzotriazole-1-methanol

98%

Synonym: 1-(Hydroxymethyl)benzotriazole, 1-Benzotriazolemethanol, NSC 12463

  • CAS Number 28539-02-8

  • Empirical Formula (Hill Notation) C7H7N3O

  • Molecular Weight 149.15

  •  MDL number MFCD00179118

  •  PubChem Substance ID 24865702

  •  NACRES NA.22

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Properties

Related Categories C-C Bond Formation, Chemical Synthesis, Other Synthetic Reagents for C-C Bond Formation, Synthetic Reagents
Quality Level   100
assay   98%
reaction suitability   reaction type: C-C Bond Formation
mp   150-152 °C (lit.)
SMILES string   OCn1nnc2ccccc12
InChI   1S/C7H7N3O/c11-5-10-7-4-2-1-3-6(7)8-9-10/h1-4,11H,5H2
InChI key   MXJIHEXYGRXHGP-UHFFFAOYSA-N

Description

Application

Catalyst for:
• Hydrolysis of phenyl esters of a-furoic acid

Used as:
• Corrosion inhibitor of iron in aerated acidic media
• Reactive oxygen scavenger

Reactant for:
• Synthesis of hydroxy-skipped bis-homo-inositols as potential glycosidase inhibitors via Sharpless asymmetric dihydroxylation and substrate-directed anionic hydroxymethylation
• Enantioselective synthesis of aplysin utilizing a palladium-catalyzed addition of an arylboronic acid to an allenic alcohol, followed by Eschenmoser/Claisen rearrangement
• Synthesis of substituted dihydroquinoline carboxylic acids as antitumor and HIV-1 integrase inhibitors
• Gosteli-Claisen rearrangement

Safe reagent for the in situ generation of anhydrous formaldehyde in organic solvents.

Packaging

10, 50 g in glass bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Target organs 
Respiratory system
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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