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412449 Sigma-Aldrich

PAMAM dendrimer, ethylenediamine core, generation 4.0 solution

10 wt. % in methanol

Synonym: Starburst Generation 4

  • CAS Number 163442-67-9

  • Linear Formula [NH2(CH2)2NH2]:(G=4);dendri PAMAM(NH2)64

  • Molecular Weight 14214.17

  •  MDL number MFCD00197936

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Properties

Related Categories Amino Surface Groups, Dendrimers, Materials Science, Nanomaterials, PAMAM Dendrimers More...
description   amino surface groups
form   10 wt.% in methanol
mol wt   generation 4.0
feature   core type ethylenediamine core (2-carbon core)
concentration   10 wt. % in methanol
no. Surface Groups   64
refractive index   n20/D 1.348
bp   64.7 °C
density   0.813 g/mL at 25 °C
storage temp.   2-8°C

Description

General description

PAMAM dendrimer, ethylenediamine core, generation 4.0 solution is a poly(amidoamine) that is categorized as a class of dendritic polymers which can be prepared by a two-step interactive reaction that forms generations around the central ethylenediamine core. It consists of nitrogen and amide as functional groups that are structured in regular “branched upon branched” pattern. It is majorly used as a high capacity chelating agent.

Application

PAMAM dendrimer, ethylenediamine core, generation 4.0 solution is used as a compacting agent to bring in the conformational changes in the DNA molecule. It can be attached on the cellulose substrate that acts as a biofunctional surface for potential applications in immonoassays. It is used in MRI contrast agents and in the condensation formation of silica nanospheres.

Packaging

2.5, 10 g in glass bottle

Physical form

Contains 64 surface primary amino groups

Legal Information

Manufactured by Dendritech®, Inc.

Dendritech is a registered trademark of Dendritech, Inc.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Eyes
RIDADR 
UN1230 - class 3 - PG 2 - Methanol, solution
WGK Germany 
WGK 3
Flash Point(F) 
51.8 °F - closed cup - Not applicable
Flash Point(C) 
11 °C - closed cup - Not applicable
Protocols & Articles

Articles

Solubility Enhancement of Poorly Water Soluble Molecules using Dendrimers

Environmental concerns are driving the replacement of volatile organic solvents by water and aqueous mixtures. This change often creates challenges because many organic molecules show low water solub...
Dr. Abhay Singh ChauhanDr.Sonke SvensonDr. Lori Reyna andDr. Donald Tomalia
Material Matters 2007, 2.1, 24.
Keywords: Anti-inflammatory agents, Bacterial conjugations, Cancer, Catalysis, Dialysis, Environmental, Inductively coupled plasma, Solvents, Spectroscopy

Peer-Reviewed Papers
15

References

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