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47633 Sigma-Aldrich

Fmoc-Leu-OH

≥97.0%

Synonym: N-(9-Fluorenylmethoxycarbonyl)-L-leucine, Fmoc-L-leucine

  • CAS Number 35661-60-0

  • Empirical Formula (Hill Notation) C21H23NO4

  • Molecular Weight 353.41

  •  Beilstein/REAXYS Number 2178254

  •  EC Number 252-662-7

  •  MDL number MFCD00037133

  •  eCl@ss 32160406

  •  PubChem Substance ID 57651051

  •  NACRES NA.26

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Properties

Related Categories Amino Acids & Derivatives, Catalysis and Inorganic Chemistry, Chemical Biology, Chemical Synthesis, Leucine,
Quality Level   100
assay   ≥97.0%
optical activity   [α]20/D −25±2°, c = 1% in DMF
mp   152-156 °C (lit.)
  152-156 °C
functional group   amine
  carboxylic acid
reaction suitability   reaction type: C-H Activation
  reagent type: ligand
reaction type: Peptide Synthesis
storage temp.   2-8°C
SMILES string   CC(C)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
InChI   1S/C21H23NO4/c1-13(2)11-19(20(23)24)22-21(25)26-12-18-16-9-5-3-7-14(16)15-8-4-6-10-17(15)18/h3-10,13,18-19H,11-12H2,1-2H3,(H,22,25)(H,23,24)/t19-/m0/s1
InChI key   CBPJQFCAFFNICX-IBGZPJMESA-N

Description

Packaging

5, 50 g in glass bottle

Biochem/physiol Actions

PPARγ ligand that induces insulin sensitization, but not adipogenesis.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Natural Amino Acid Building Blocks for Peptide Synthesis

With a growing peptide drug market the fast, reliable and uncomplicated synthesis of peptides is of paramount importance.1 Today, the most common synthetic approaches to medium and even large peptide...
Matthias Junkers
ChemFiles 2008, 8.7, 22.
Keywords: Building blocks, Peptide synthesis, Peptidomimetics, Solid phase peptide synthesis

Peer-Reviewed Papers
15

References

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