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  • 552151 - D-Glucose-13C6,1,2,3,4,5,6,6-d7

552151 Sigma-Aldrich


99 atom % 13C, 97 atom % D

Synonym: D-Glucose-13C6,C-d7, Deuterated Glucose, Dextrose-13C6,C-d7, Labeled Glucose

  • CAS Number 201417-01-8

  • Empirical Formula (Hill Notation) 13C6H5D7O6

  • Molecular Weight 193.15

  •  MDL number MFCD00274634

  •  PubChem Substance ID 329758091

  •  NACRES NA.12



Related Categories Alphabetical Listings, Biomolecular NMR, Carbohydrates, G-H, Metabolic Labeling,
Quality Level   200
isotopic purity   99 atom % 13C
  97 atom % D
assay   99% (CP)
form   powder
optical activity   [α]25/D +52.0°, c = 2 in H2O (trace NH4OH)
mp   150-152 °C (lit.)
mass shift   M+13
SMILES string   [2H][13C](=O)[13C@]([2H])(O)[13C@@]([2H])(O)[13C@]([2H])(O)[13C@]([2H])(O)[13C]([2H])([2H])O
InChI   1S/C6H12O6/c7-1-3(9)5(11)6(12)4(10)2-8/h1,3-6,8-12H,2H2/t3-,4+,5+,6+/m0/s1/i1+1D,2+1D2,3+1D,4+1D,5+1D,6+1D


General description

D- Glucose is a monosaccharide (simple sugar). It is a vital source of energy for living organisms. It exists in a cyclic form, containing six carbon atoms. It is present naturally in all plants and fruits in free or bound state. It is synthesized by the process, gluconeogenesis, in the liver and kidney.


1, 5 g in glass bottle

Biochem/physiol Actions

D-Glucose is involved in the metabolic processes, such as glycolysis and Kreb’s cycle for the generation of adenosine triphosphates. It is stored in the form of glycogen in liver. D-Glucose moieties constitutes to form cellulose by β-1,4-glycosidic linkage.


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Safety & Documentation

Safety Information

Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Protocols & Articles


13C MRS to Probe Brain Metabolism Using Hyperpolarized Pyruvic Acid

Cerebral function depends on coordinated interactions between two distinct cell types, namely neurons and astrocytes (also called glial cells), and relies on high metabolic activity that is supported...
Keywords: Central Nervous System, Citric Acid Cycle, Clinical, Electron spin resonance, Glycolysis, Magnetic resonance imaging, Magnetic resonance spectroscopy, Metabolic Pathways, Metabolism, Metabolites, Neurotransmission, Neurotransmitters, Oncology, Oxidations, Spectroscopy

Glycolysis via the Embden-Meyerhof-Parnas glycolytic pathway

Glycolysis is the almost universal pathway that converts glucose into pyruvate along with the formation of nicotinamide adenine dinucleotide (NADH) and adenosine triphosphate (ATP). It primarily occu...
Keywords: Aerobic, Aldol reaction, Anaerobic, Dehydration reaction, Fermentation, Glycolysis, Isomerizations, Metabolism, Metabolites, Metabolomics, Oxidations, Phosphorylations, Photosynthesis

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Diminish lag time by > 60% and the number of hours required to attain high cell density by > 45% with the inclusion of 10% ISOGRO in M9.
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Isotopic Labeling in Solid-state NMR of Proteins

ISOTEC Stable Isotopes: Resonating with the Advancing Field of Biomolecular NMR (1.21 Mb PDF)
Francesca M. Marassi, Ph.D.
ISOTEC® Stable Isotopes: Resonating with the Advancing Field of Biomolecular NMR, 2–3
Keywords: Asymmetric synthesis, Molecular biology, Nuclear magnetic resonance spectroscopy, Spectroscopy

Monosaccharide Biosynthesis

Each monosaccharide has its own interesting metabolism. The pathway by which a monosaccharide is made, is not the reverse of its degradation pathway (see Figure 4).
BioFiles 2007, 2.6, 21.
Keywords: Addition reactions, Carboxylations, Catalysis, Condensations, Decarboxylations, Degradations, Metabolic Pathways, Metabolism, Metabolites, Phosphorylations, Reductions

Solid-state NMR on Larger Biomolecules

In the last years, remarkable progress has been made to probe molecular structure of biological systems using Magic Angle Spinning solid-state NMR (ssNMR). Prominent examples relate to research areas...
Marc Baldus
ISOTEC® Stable Isotopes: Products for Solid State NMR, 2010, 2–4
Keywords: Atomic absorption spectroscopy, Biochemistry, Biological processes, Catalysis, Cell biology, Gene expression, Mass spectrometry, Materials Science, Microscopy, Molecular biology, Nuclear magnetic resonance spectroscopy, Photosynthesis, Polymorphisms, Reductions, Research areas, Sample preparations, Scanning electron microscopy

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