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  • 686638 - Polyester-16-hydroxyl-1-acetylene bis-MPA dendron, generation 4

686638 Sigma-Aldrich

Polyester-16-hydroxyl-1-acetylene bis-MPA dendron, generation 4


Synonym: Dendron-G4-Acetylene-OH

  • Empirical Formula (Hill Notation) C78H124O46

  • Molecular Weight 1797.79

  •  MDL number MFCD18426583

  •  PubChem Substance ID 329761062

  •  NACRES NA.23



Related Categories Dendrimers, Dendrons, Materials Science, Nanomaterials
Quality Level   100
description   hydroxyl surface groups
assay   96%
form   powder (lyophilized)
mol wt   generation 4
feature   focal point acetylene
no. Surface Groups   16
storage temp.   2-8°C
InChI   1S/C78H124O46/c1-17-18-110-57(103)72(10,35-119-62(108)77(15,45-121-58(104)73(11,37-111-49(95)64(2,19-79)20-80)38-112-50(96)65(3,21-81)22-82)46-122-59(105)74(12,39-113-51(97)66(4,23-83)24-84)40-114-52(98)67(5,25-85)26-86)36-120-63(109)78(16,47-123-60(106)75(13,41-115-53(99)68(6,27-87)28-88)42-116-54(100)69(7,29-89)30-90)48-124-61(107)76(14,43-117-55(101)70(8,31-91)32-92)44-118-56(102)71(9,33-93)34-94/h1,79-94H,18-48H2,2-16H3


General description

Soluble in a variety of solvents, such as THF, DMSO, DMF, methanol, and water.

calculated mol. wt. 1,798


250 mg in glass insert

Other Notes

Bis-MPA = 2,2-Bis(hydroxyl-methyl)propionic acid

Legal Information

Manufactured by Polymer Factory Sweden AB

Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Flash Point(F) 
>212 °F
Flash Point(C) 
>100 °C
Protocols & Articles


Biocompatible Dendritic Building Blocks for Advanced Biomedical Research

Dendrimers and dendrons are symmetrically branched polymer structures that possess a well-defined spatial distribution of functional groups. These dendritic materials have attracted considerable inte...
1Dr. Michael Malkoch and 2Dr. Andreas M. Nyström
Material Matters, 2012 v7, n3
Keywords: Applications, Asymmetric synthesis, Bacterial conjugations, Building blocks, Cancer, Catalysis, Chemical reactions, Click chemistry, Diagnostic, Diagnostic Imaging, Materials Science, Nanomaterials, Solvents, Type

Dendrons and Hyperbranched Polymers: Multifunctional Tools for Materials Chemistry

Dendrimers are polymeric macromolecules composed of multiple perfectly-branched monomers radially emanating from a central core (Figure 1). The number of branch points increases upon moving from the ...
Keywords: Biomaterials, Catalysis, Chemistry research, Click chemistry, Cycloadditions, Degradations, Polymerization reactions, Solvents


Core functionalization of Polyester-16-hydroxyl-1-acetylene bis-MPA dendron

Theoretical MW: 1797.79 g/mol Average Molecular Formula: C78H124O46 Number of hydroxyl groups: 16 Number of acetylene groups: 1
Keywords: Catalysis, Chromatography, Click chemistry, Cycloadditions, Flash chromatography, Nuclear magnetic resonance spectroscopy, Solvents

Core functionalization of Polyester-32-hydroxyl-1-acetylene bis-MPA dendron

This monodisperse compound has multiple surface hydroxyl groups and a single alkyne focal point function. The alkyne function is well suited for “Click chemistry” catalytic cycloaddition to azides (s...
Keywords: Catalysis, Chromatography, Click chemistry, Cycloadditions, Flash chromatography, Nuclear magnetic resonance spectroscopy, Solvents

Related Content

Dendritic Polyester Scaffolds for Drug Delivery Applications

Dendrimers and dendrons are highly branched polymer structures with a precise distribution of functional groups. In contrast to their linear analogues, they are monodisperse in nature and present no ...
Sandra García-Gallego
Marie Sklowdoska-Curie Researcher at KTH Royal Institute of Technology, and Michael Malkoch, Associate Professor at KTH Royal Institute of Technology and Chief Executive Officer at Polymer Factory Sweden AB
Keywords: Antibiotics, Bacterial conjugations, Building blocks, Catalysis, Chemical reactions, Chromatography, Click chemistry, Column chromatography, Esterifications, Green chemistry, Nuclear magnetic resonance spectroscopy, Purification, Solvents

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