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719927 Sigma-Aldrich

Resomer® RG 756 S, Poly(D,L-lactide-co-glycolide)

ester terminated, lactide:glycolide 75:25, Mw 76,000-115,000

Synonym: PLGA

  • CAS Number 26780-50-7

  • Linear Formula [C3H4O2]x[C2H2O2]y

  •  NACRES NA.23

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Properties

Related Categories 3D Printing Materials for Research and Development, 75:25 (Lactide:Glycolide), Biodegradable Polymers, Biodegradeable Polymers for 3D Printing, Lactide and Glycolide Polymers,
Quality Level   200
form   amorphous
feed ratio   lactide:glycolide 75:25
mol wt   Mw 76,000-115,000
degradation timeframe   <6 months
viscosity   0.71-1.0 dL/g, 0.1 % (w/v) in chloroform(25 °C, Ubbelohde) (size 0c glass capillary viscometer)
transition temp   Tg 49-55 °C
storage temp.   2-8°C
InChI   1S/C6H8O4.C4H4O4/c1-3-5(7)10-4(2)6(8)9-3;5-3-1-7-4(6)2-8-3/h3-4H,1-2H3;1-2H2
InChI key   LCSKNASZPVZHEG-UHFFFAOYSA-N

Description

Application

Controlled release

Poly (lactic-co-glycolic acid) 75:25 copolymer may be used to design a controlled drug delivery implant.

Packaging

5 g in glass bottle

Legal Information

Product of Evonik

RESOMER is a registered trademark of Evonik Rohm GmbH

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

3D Printing of Carbon Fiber-Reinforced Composites

3D printing is a type of additive manufacturing that can be used to rapidly fabricate components with highly customizable geometries, most typically using a layer-by-layer fabrication process. 3D pri...
Zhenyu Bo* (Ph.D Candidate at Northwestern University) and Jia Choi*, PhD, Product Manager


*Materials Science Product Management Team, MilliporeSigma, Milwaukee, WI.
Keywords: Deposition, Nanomaterials, Nanotubes

Biodegradable Aliphatic Polyesters for Drug Delivery

1Department of Chemistry and Biochemistry, University of Texas at Dallas, Richardson, TX 75080 2Department of Bioengineering, University of Texas at Dallas, Richardson, TX 75080 *Email: mihaela@utdal...
Vasanthy Karmegam,1 Pooneh Soltantabar,2 Erika Joy L. Calubaquib,1 Ruvanthi N. Kularatne,1 Mihaela C. Stefan1,2*
Material Matters, 2017, 12.2
Keywords: Bacterial conjugations, Biochemistry, Cancer, Catalysis, Clinical, Degradations, Electron spin resonance, Polymerization reactions, Reductions, Ring-opening polymerization, Solvents, Vitamins

Biodegradable Polyester Based Nanoparticle Formation by Miniemulsion Technique

Aliphatic polyesters such as polylactide, poly(lactide-co-glycolide) and polycaprolactone, as well as their copolymers, represent a diverse family of synthetic biodegradable polymers that have been w...
Anna Musyanovych and Katharina Landfester
Material Matters 2012 v7, n3
Keywords: Adhesion, Antitumor agents, Biomaterials, Central Nervous System, Degradations, Deposition, Diffusion, Evaporation, Growth factors, Melting, Microscopy, Precipitation, Purification, Reductions, Scanning electron microscopy

Biodegradable Polyester-based Nanoparticle Formation by Miniemulsion Technique

Anna Musyanovych and Katharina Landfester Max Planck Institute for Polymer Research, Ackermannweg 10, 55128 Mainz, Germany Email: landfest@mpip-mainz.mpg.de
Keywords: Adhesion, Antitumor agents, Biomaterials, Central Nervous System, Degradations, Deposition, Diffusion, Evaporation, Growth factors, Melting, Microscopy, Precipitation, Purification, Reductions, Scanning electron microscopy

Biodegradable Polymers

Polymers with controlled biomedical degradation characteristics can be used as an important part of tissue engineering and drug delivery therapies. Many types of natural and synthetic biodegradable p...
Keywords: Degradations, High performance liquid chromatography, Hydration reaction, Melting, Pharmaceutical, Polymerization reactions, Ring-opening polymerization, Solvents

Biomaterials Tutorial

Biocompatible Polymers Biodegradable Polymers Crosslinkers Biocompatible Inorganic Materials Supramolecular Chemistry
Keywords: Agriculture, Antimicrobials, Biomaterials, Ceramics, Chromatography, Cosmetics, Degradations, Diffusion, Environmental, Genomics, Germination, Nanomaterials, Oxidations, Petrochemical, Pharmaceutical, Polymerization reactions, Proteomics, Reductions

Bioprinting for Tissue Engineering and Regenerative Medicine

Chi-Chun Pan,1,2 Arnaud Bruyas,1 Yunzhi Peter Yang1,3,4 Departments of 1Orthopedic Surgery, 2Mechanical Engineering, 3Materials Science and Engineering, and 4Bioengineering Stanford University, 300 P...
Chi-Chun Pan, Arnaud Bruyas, Yunzhi Peter Yang
Material Matters, 2016, 11.2
Keywords: Biomaterials, Cancer, Cell attachment, Clinical, Deposition, Growth factors, Pharmaceutical

Poly(Glycerol Sebacate) in Tissue Engineering and Regenerative Medicine

Yadong Wang,1 Steven Lu,2 Peter Gabriele,2 Jeremy J. Harris2* 1Department of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15261 USA 2Research and Development, The Secant Group, LLC, Telfo...
Yadong Wang, Steven Lu, Peter Gabriele, Jeremy J. Harris
Material Matters, 2016, 11.3
Keywords: Antimicrobials, Biomaterials, Building blocks, Cardiovascular, Clinical, Confocal microscopy, Degradations, Ligands, Metabolites, Microscopy, Oxidations, Pharmaceutical, Polymerization reactions, Positron Emission Tomography, Reversed-phase chromatography, Solvents, Titrations, transformation

RESOMER® - Biodegradable Polymers for Sutures, Medical Devices, Drug Delivery Systems and Tissue Engineering

The ability for synthetic polymers to degrade in a controlled manner was developed for environmental reasons in the late 1960s. Interest in utilizing biodegradable polymers for biomedical application...
Keywords: Cancer, Degradations, Diagnostic, Diffusion, Environmental, Evaporation, Hormones, PEGylations, Polymerization reactions, Reductions, Ring-opening polymerization, Separation

Peer-Reviewed Papers
15

References

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