EMAIL THIS PAGE TO A FRIEND
C85778 Sigma-Aldrich

o-Cresolphthalein

indicator grade

  • CAS Number 596-27-0

  • Empirical Formula (Hill Notation) C22H18O4

  • Molecular Weight 346.38

  •  Beilstein/REAXYS Number 310554

  •  EC Number 209-881-8

  •  MDL number MFCD00005912

  •  PubChem Substance ID 24893078

  •  NACRES NA.47

Purchase

Properties

Related Categories Analytical Reagents, Analytical/Chromatography, C, Cell Biology, Hematology and Histology,
grade   indicator grade
form   powder
application(s)   hematology: suitable
  histology: suitable
  titration: suitable
pH range   8.2 - 9.8, colorless to red
mp   219-221 °C (lit.)
λmax   381 nm (2nd)
  566 nm
ε (extinction coefficient)   ≥10000 at 294-300 nm
  ≥39000 at 564-570 nm
  ≥5000 at 378-384 nm
Featured Industry   Diagnostic Assay Manufacturing
storage temp.   room temp
SMILES string   Cc1cc(ccc1O)C2(OC(=O)c3ccccc23)c4ccc(O)c(C)c4
InChI   1S/C22H18O4/c1-13-11-15(7-9-19(13)23)22(16-8-10-20(24)14(2)12-16)18-6-4-3-5-17(18)21(25)26-22/h3-12,23-24H,1-2H3
InChI key   CPBJMKMKNCRKQB-UHFFFAOYSA-N

Description

Application

O-Cresolphthalein has been used as a component in calcifying media for calcification assay.

Packaging

10 g in glass bottle

Biochem/physiol Actions

o-Cresolphthalein is a reversible pH indicator. The kinetics of the reverse pathway (red-purple to colorless) is slow, thereby making it an appropriate molecule to check flow patterns in ducts with corrugated walls. It is also used for the colorimetric determination of calcium content via the o-cresolphthalein complexone method. Binding of calcium to o-cresolphthalein, in the presence of alkaline conditions (pH 10-12), results in the formation of a red complex with an absorbance at 570-575nm.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

Please Enter a Lot Number

Certificate of Origin (COO)

Please Enter a Lot Number
Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?