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F3401 Aldrich

2-Fluoroaniline

≥99%

Synonym: 1-Amino-2-fluorobenzene

  • CAS Number 348-54-9

  • Linear Formula FC6H4NH2

  • Molecular Weight 111.12

  •  Beilstein Registry Number 1524219

  •  EC Number 206-478-9

  •  MDL number MFCD00007642

  •  PubChem Substance ID 24894844

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Properties

InChI Key   FTZQXOJYPFINKJ-UHFFFAOYSA-N
assay   ≥99%
refractive index   n20/D 1.544(lit.)
bp   182-183 °C(lit.)
mp   −29 °C(lit.)
density   1.151 g/mL at 25 °C(lit.)

Description

Packaging

25, 100, 500 g in glass bottle

Biochem/physiol Actions

The metabolism and excretion of the xenobiotic compound 2-fluoroaniline is important due to human exposure in manufacturing. It is found to be very efficiently metabolized, primarily by 4-hydroxylation with subsequent sulfate or glucuronide formation. N-Acetylation is also observed. At least 80% of the dose is excreted in the urine within 24 hr. 2-Fluoroaniline exerts its nephrotoxic effect through 4-hyroxylation and subsequent p-benzoquinonimine formation.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2941 6.1 / PGIII
WGK Germany 
3
Flash Point(F) 
140 °F
Flash Point(C) 
60 °C

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Protocols & Articles
Peer-Reviewed Papers
15

References

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