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G10806 Sigma-Aldrich

Gramine

99%

Synonym: 3-(Dimethylaminomethyl)indole, Donaxine, NSC 16892

  • CAS Number 87-52-5

  • Empirical Formula (Hill Notation) C11H14N2

  • Molecular Weight 174.24

  •  Beilstein/REAXYS Number 140521

  •  EC Number 201-749-8

  •  MDL number MFCD00005629

  •  PubChem Substance ID 24895037

  •  NACRES NA.22

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Properties

Related Categories Building Blocks, C11, Cell Biology, Chemical Synthesis, Heterocyclic Building Blocks,
assay   99%
mp   132-134 °C (lit.)
SMILES string   CN(C)Cc1c[nH]c2ccccc12
InChI   1S/C11H14N2/c1-13(2)8-9-7-12-11-6-4-3-5-10(9)11/h3-7,12H,8H2,1-2H3
InChI key   OCDGBSUVYYVKQZ-UHFFFAOYSA-N

Description

Application

Reactant for preparation of:
• Dopamine D2 receptor antagonists
• Anti-malarial drugs
• 5-indolyl-Mannich bases
• Proliferation inhibitors
• Inhibitors of human mast cell chymase
• Preparation of DL-tryptophan
• Potential detoxification inhibitors of the crucifer phytoalexin brassinin
• 3-vinylindoles
• Serotonin 5-HT6 receptor ligand templates
• Selective protein kinase c delta (PKCδ) down regulators

Packaging

25 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
NL7525000
Flash Point(F) 
332.6 °F
Flash Point(C) 
167 °C

Documents

Certificate of Analysis (COA)

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Meet Synthia - Retrosynthesis Sofware
Protocols & Articles

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers
15

References

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