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850304P Avanti

05:0 PC

1,2-dipentanoyl-sn-glycero-3-phosphocholine, powder

Synonym: 1,2-divaleryl-sn-glycero-3-phosphocholine; PC(5:0/5:0)

  • CAS Number 66414-34-4

  • Empirical Formula (Hill Notation) C18H36NO8P

  • Molecular Weight 425.45

  •  NACRES NA.25

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Properties

Related Categories Avanti PC & LPC, Avanti Phospholipids, Avanti Polar Lipids Products, Biochemicals and Reagents, Lipids More...
assay   >99% (TLC)
form   powder
packaging   pkg of 1 × 25 mg (850304P-25mg)
mfr. no.   Avanti Polar Lipids, 850304P
shipped in   dry ice
storage temp.   −20°C
SMILES string   [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCC)=O)COC(CCCC)=O)=O

Description

General description

Phosphatidylcholine (PC) is mucosal layer constituent, which can serve as a surfactant.

The list of Phosphatidylcholine products offered by Avanti is designed to provide compounds having a variety of physical properties. Products available include short chain (C3-C8 are water soluble and hygroscopic), saturated, multi-unsaturated and mixed acid PC′s. All of the products are purified by HPLC, and special precautions are taken to protect the products for oxidization and hydrolysis.

Application

05:0 PC (D5PC/1,2-dipentanoyl-sn-glycero-3-phosphocholine) may be used:
• as a component in the preparation of endophilin Bin−Amphiphysin−Rvs domain (EndoBAR) deforms membranes
• in binary mixtures to study the effects of lipid chain length and unsaturation on bicelles stability
• in the preparation of homo and heterooligomers for ESi MSMS studies

Biochem/physiol Actions

Phosphatidylcholine (PC) is known to participate in fusion and transport of membranes. It plays a key role in endocytosis and the catalytic activity of enzymes.

Packaging

5 mL Clear Glass Sealed Ampule (850304P-25mg)

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

Critical Micelle Concentrations (CMCs) - Avanti® Polar Lipids

The critical micelle concentration (CMC) can be approximately defined as the lipid monomer concentration at which appreciable amounts (>5% of total) of micellar aggregates first begin to appear in th...
Keywords: Biochemistry

Storage & Handling of Lipids - Avanti® Polar Lipids

The following statements pertain specifically to Avanti’s lipid products for research and should not necessarily be applied to cGMP lipids intended for pharmaceutical or diagnostic applications.
Keywords: Diagnostic, Oxidations, Pharmaceutical, Solvents

Protocols

Determination of Phospholipid Oxidation by UV/VIS Spectroscopy - Avanti® Polar Lipids

The percent oxidation of a phospholipid can be determined by using Beer’s Law to calculate the peroxidized phospholipid’s concentration from its absorbance at 234 nm.
Keywords: Extinction coefficient, Oxidations

General Lipid/BSA Solubilization Protocol For Cell Delivery

Water Solutions: Solubilizing some lipids is difficult using organic solvents. Typically, lipids are suspended in methanol to aliquot, the methanol is then dried and the residue dispersed using fatty...
Keywords: Evaporation, Solvents

Peer-Reviewed Papers
15

References

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