• USA Home
  • 1.52021 - Chromolith® HighResolution RP-18 endcapped 50-4.6 HPLC column

EMAIL THIS PAGE TO A FRIEND
1.52021 Supelco

Chromolith® HighResolution RP-18 endcapped 50-4.6 HPLC column

Purchase

Properties

Related Categories Analytical/Chromatography, HPLC/UHPLC More...
Quality Level   100
feature   endcapped
parameter   200 bar pressure
  45 °C max. temp.
application(s)   HPLC: suitable
  mass spectrometry (MS): suitable (High)
matrix   highly porous
  monolithic
pore size   1.15 μm macroporosity
  15 nm mesoporosity
operating pH range   2 - 7.5
storage conditions   no restrictions.

Description

General description

All Chromolith® HighResolution columns are made of monolithic silica with a characteristic bimodal pore structure. Chromolith 4.6 mm columns have macropores with 1.15 µm diameter, giving a column efficiency exceeding 135,000 plates/meter. The mesopores are 15 nm (150 Å), the surface modification is octadecylsilan with full end-capping.

Analysis Note

Pressure: 15 - 50 bar
Performance (anthracene)
Theoretical Plates (N/m) (Anthracene): ≥ 135000
Capacity factor (Anthracene): 3.2 - 4.2
Tailing (USP): 0.90 - 1.35 %
Selectivity
separation factor (anthracene/progesterone): 1.90 - 2.35

Legal Information

Chromolith is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety & Documentation

Safety Information

Safety Information for this product is unavailable at this time.
Protocols & Articles

Articles

Chromolith® HPLC and UHPLC columns

Chromolith® HPLC and UHPLC columns are made from monolithic silica with a bimodal pore structure using sol-gel technology. There are no silica particles.
Keywords: High performance liquid chromatography, Sample preparations, Separation, Sol-gel

HPLC Analysis of Albuterol Tablets - Assay on Chromolith HighResolution RP-18 endcapped 50 x 4.6mm

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Albuterol Tablets - Assay on Chromolith HighResolution RP-18 endcapped 50 x 4.6mm
Keywords: High performance liquid chromatography, Pharmaceutical, Sample preparations

HPLC Analysis of Finasteride Tablets on Chromolith® HighResolution RP-18 endcapped 50 x 4.6mm

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Finasteride Tablets on Chromolith® HighResolution RP-18 endcapped 50 x 4.6mm
Keywords: High performance liquid chromatography, Pharmaceutical, Sample preparations

HPLC Analysis of Olmesartan Medoxomil, Amlodipine Besylate, and Hydrochlorothiazide Tablet on Chromolith® High Resolution RP-18e

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Olmesartan Medoxomil, Amlodipine Besylate, and Hydrochlorothiazide Tablet on Chromolith® High Resolution RP-18e
Keywords: High performance liquid chromatography, Pharmaceutical

HPLC Analysis of Simvastatine USP on Chromolith High Resolution RP-18e (analyte set 2)

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Simvastatine USP on Chromolith High Resolution RP-18e (analyte set 2)
Keywords: High performance liquid chromatography, Pharmaceutical, Sample preparations

HPLC Analysis of Spironolactone on Chromolith® HighResolution RP-18 endcapped 50 x 4.6 mm

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Spironolactone on Chromolith® HighResolution RP-18 endcapped 50 x 4.6 mm
Keywords: High performance liquid chromatography

HPLC Analysis of Tolvaptan Assay on Chromolith® High Resolution RP-18e

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tolvaptan Assay on Chromolith® High Resolution RP-18e
Keywords: High performance liquid chromatography, Pharmaceutical

Monolithic Silica with Bimodal Pore Structure

Thanks to their patented monolithic silica technology, Chromolith® HPLC columns allow you to race through separations with maximum robustness and selectivity—at minimal back pressure.
Keywords: Filtration, High performance liquid chromatography, Precipitation, Sample preparations, Separation, Sol-gel, Solid phase extractions

Related Content

Supelco HPLC Calculator for Isocratic or Gradient Method Transfer

Calculates conditions for transfer of an isocratic or gradient method from one HPLC column to another. Allows method scaling from microbore through preparative column range. Calculates time and solve...
Keywords: High performance liquid chromatography

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?