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03-5330 Sigma-Aldrich

γ-Butyrolactone

SAJ first grade, ≥99.5%

Synonym: γ-Hydroxybutyric acid lactone, 4-Hydroxybutyric acid lactone, GBL

  • CAS Number 96-48-0

  • Empirical Formula (Hill Notation) C4H6O2

  • Molecular Weight 86.09

  •  Beilstein/REAXYS Number 105248

  •  MDL number MFCD00005386

  •  PubChem Substance ID 329747730

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Properties

Related Categories Building Blocks, Carbonyl Compounds, Cell Biology, Chemical Synthesis, Lactones,
grade   SAJ first grade
vapor density   3 (vs air)
vapor pressure   1.5 mmHg ( 20 °C)
InChI Key   YEJRWHAVMIAJKC-UHFFFAOYSA-N
assay   ≥99.5%
autoignition temp.   851 °F
expl. lim.   16 %
availability   available only in Japan
refractive index   n20/D 1.436 (lit.)
bp   204-205 °C (lit.)
mp   −45 °C (lit.)
density   1.12 g/mL at 25 °C (lit.)

Description

Biochem/physiol Actions

Precursor of γ-hydroxybutyric acid (GHB). It blocks dopamine release by blocking impulse flow in dopaminergic neurons. Pretreatment with γ-butyrolactone allows detection of autoreceptor-induced dopamine release.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
Protocols & Articles
Peer-Reviewed Papers
15

References

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