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00302 Sigma-Aldrich

Citrinin

from Penicillium citrinum, ≥98.0% (TLC)

Synonym: 4,6-Dihydro-8-hydroxy-3,4,5-trimethyl-6-oxo-3H-2-benzopyran-7-carboxylic acid

  • CAS Number 518-75-2

  • Empirical Formula (Hill Notation) C13H14O5

  • Molecular Weight 250.25

  •  Beilstein Registry Number 5282243

  •  EC Number 208-257-2

  •  MDL number MFCD00006912

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Properties

biological source   Penicillium citrinum
InChI Key   CQIUKKVOEOPUDV-IYSWYEEDSA-N
assay   ≥98.0% (TLC)
storage temp.   2-8°C

Description

Biochem/physiol Actions

A mycotoxin found in grains and animal feed that nephrotoxic and is a teratogen in rodents, reducing blastocyst cell number, embryonic survival, and neonatial weight and increasing fetal abnormalities. It′s cytotoxicity to cells in culture are associated with the production of reactive oxygen species, the activation of mitochondrial apoptotic pathways, and the inhibition of antiapoptotic phosphorylation pathways.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
RTECS 
DJ2275000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

replaced by

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Description

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C1017 Citrinin, from Penicillium citrinum, ≥98% (HPLC)

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