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Hesperidin

primary reference standard

Synonym: 3′,5,7-Trihydroxy 4′-methoxyflavanone 7-rutinoside, Hesperetin 7-rhamnoglucoside, Hesperitin-7-rutinoside

  • CAS Number 520-26-3

  • Empirical Formula (Hill Notation) C28H34O15

  • Molecular Weight 610.56

  •  Beilstein/REAXYS Number 75140

  •  EC Number 208-288-1

  •  MDL number MFCD00075663

  •  PubChem Substance ID 329747968

  •  NACRES NA.24

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Flavonoids, Phyto Primary Reference Standards and Extracts (Secondary Reference Standards), Phytochemical Standards More...
grade   primary reference standard
CofA   certificate is enclosed in each package
shelf life   limited shelf life, expiry date on the label
mp   250-255 °C (dec.) (lit.)
Featured Industry   Food and Beverages
SMILES string   COc1ccc(cc1O)[C@@H]2CC(=O)c3c(O)cc(O[C@@H]4O[C@H](CO[C@@H]5O[C@@H](C)[C@H](O)[C@@H](O)[C@H]5O)[C@@H](O)[C@H](O)[C@H]4O)cc3O2
InChI   1S/C28H34O15/c1-10-21(32)23(34)25(36)27(40-10)39-9-19-22(33)24(35)26(37)28(43-19)41-12-6-14(30)20-15(31)8-17(42-18(20)7-12)11-3-4-16(38-2)13(29)5-11/h3-7,10,17,19,21-30,32-37H,8-9H2,1-2H3/t10-,17-,19+,21-,22+,23+,24-,25+,26+,27+,28+/m0/s1
InChI key   QUQPHWDTPGMPEX-QJBIFVCTSA-N

Description

General description

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Application

Studies of the behavior of hesperidin and hesperetin (the aglycone) with DMPC liposomes find the aglycone penetrates more deeply and binds more strongly to the "membrane." This may explain the better bioavailability of bioflavonoid aglycones in general.

Reference Standard in the analysis of herbal medicinal products

Biochem/physiol Actions

Flavonoid phytochemical extracted from citrus species. It is the rhamnoglucoside (rutinoside) of hesperetin.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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