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11546 Sigma-Aldrich

3′-Azido-3′-deoxythymidine

≥99.0% (HPLC)

Synonym: AZT, Azidothymidine, ZDV, Zidovudine

  • CAS Number 30516-87-1

  • Empirical Formula (Hill Notation) C10H13N5O4

  • Molecular Weight 267.24

  •  Beilstein/REAXYS Number 3595791

  •  MDL number MFCD00006536

  •  PubChem Substance ID 329749478

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Properties

biological source   synthetic
assay   ≥99.0% (HPLC)
form   powder with small lumps
impurities   ≤0.5% water
mp   113-115 °C (lit.)
solubility   H2O: 50 mg/mL, clear, colorless to slightly yellow
storage temp.   −20°C
SMILES string   CC1=CN([C@H]2C[C@H](N=[N+]=[N-])[C@@H](CO)O2)C(=O)NC1=O
InChI   1S/C10H13N5O4/c1-5-3-15(10(18)12-9(5)17)8-2-6(13-14-11)7(4-16)19-8/h3,6-8,16H,2,4H2,1H3,(H,12,17,18)/t6-,7+,8+/m0/s1
InChI key   HBOMLICNUCNMMY-XLPZGREQSA-N

Description

Biochem/physiol Actions

Reverse transcriptase inhibitor active against HIV-1 virus.

Other Notes

A potent, selective inhibitor of human immunodeficiency virus replication in MT-4 and ATH8 cells

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
XP2072000

Documents

Certificate of Analysis (COA)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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