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22128 Sigma-Aldrich

Cefotaxime sodium salt

≥98.0% (TLC)

Synonym: Cefotaxim sodium salt

  • CAS Number 64485-93-4

  • Empirical Formula (Hill Notation) C16H16N5NaO7S2

  • Molecular Weight 477.45

  •  Beilstein Registry Number 5711411

  •  EC Number 264-915-9

  •  MDL number MFCD00079073

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Properties

InChI Key   AZZMGZXNTDTSME-JUZDKLSSSA-M
assay   ≥98.0% (TLC)
impurities   ≤5% water
solubility   H2O: 50 mg/mL, clear, light yellow
Mode of action   cell wall synthesis | interferes
storage temp.   2-8°C

Description

Other Notes

Broad spectrum third generation cephalosporin antibiotic.

This product has been replaced by C7912-SIGMA | Cefotaxime sodium salt potency: 916-964 μg per mg

Biochem/physiol Actions

Cefotaxim inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs) which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell walls. As a result, bacteria lyse due to cell wall autolytic enzymes.

General description

Chemical structure: ß-lactam

Safety & Documentation

Safety Information

Symbol 
GHS08  GHS08
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
WGK Germany 
2
RTECS 
XI0250000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

replaced by

Product #

Description

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C7912 Cefotaxime sodium salt, potency: 916-964 μg per mg

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