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251275 Sigma-Aldrich

Citric acid

ACS reagent, ≥99.5%

  • CAS Number 77-92-9

  • Linear Formula HOC(COOH)(CH2COOH)2

  • Molecular Weight 192.12

  •  Beilstein Registry Number 782061

  •  EC Number 201-069-1

  •  MDL number MFCD00011669

  •  eCl@ss 39021801

  •  PubChem Substance ID 24855122

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Properties

Related Categories ACS Grade Buffers, Acids, Acids & Bases, Analytical/Chromatography, Biochemicals and Reagents,
grade   ACS reagent
InChI Key   KRKNYBCHXYNGOX-UHFFFAOYSA-N
assay   ≥99.5%
expl. lim.   8 %, 65 °F
impurities   Substances carbonizable by hot sulfuric acid, passes test
ign. residue   ≤0.02%
pKa    (1) 3.13, (2) 4.76, (3) 6.4
mp   153-159 °C (lit.)
anion traces   chloride (Cl-): ≤0.001%
  oxalate (C2O42-): passes test (limit about 0.003%)
  phosphate (PO43-): ≤0.001%
  sulfate (SO42-): ≤0.002%
cation traces   Fe: ≤3 ppm
  Pb: ≤2 ppm
Gene Information   human ... SRC(6714)

Description

Packaging

1, 2.5 kg in poly bottle

12 kg in fiber drum

5, 100, 500 g in poly bottle

Application

Citric acid has been used to prepare:
• Phosphate citrate buffer for use in enzyme-linked immunosorbent assay.
• Citrate-stabilized ceria aqueous sol, which was employed in the synthesis of cerium oxide nanoparticles.
• Citric acid-Na2HPO4-buffered stock solution for use in the determination of fecal urease activity.
• Anticoagulant citrate dextrose solution A (ACD-A), which is employed during the isolation of blood-derived endothelial progenitor cells.

Citric acid has also been used:
• In a novel process which allows controlling of the particle size during the synthesis of palladium cuboctahedrons.
• To prepare citric acid-derived carbon nanodots (CNDs) by bottom-up carbonization method.
• As a bi-component chelating agent for the synthesis of Li4Ti5O12 (lithium titanate oxide) by a novel sol–gel method.

General description

Citric acid is an organic acid commonly used as a chelating agent, a buffering agent, for pH adjustment and derivatization.

Legal Information

Redi-Dri is a trademark of Sigma-Aldrich Co. LLC

Other Notes

Go to Redi-Dri Product Listing 791725

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
GE7350000

Documents

Certificate of Analysis

Certificate of Origin


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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Protocols

Polyene-lipids: A new tool to image lipids

Lars Kuerschner a , Christer S Ejsing a , Kim Ekroos b , Andrej Shevchenko a , Kurt I Anderson a , Christoph Thiele a
Keywords: Biochemistry, Capillary electrophoresis, Cell biology, Cell culture, Cell signaling, Chromatography, Detection methods, Detergents, Genetics, Magnetic resonance spectroscopy, Mass spectrometry, Metabolism, Metabolites, Microscopy, Molecular probes, Nuclear magnetic resonance spectroscopy, Phase transitions, Reversible addition-fragmentation chain transfer polymerizations, Scanning electron microscopy, Separation, Spectroscopy, Thin layer chromatography, Wittig Reaction

State-of-the-art two-dimensional gel electrophoresis: a key tool of proteomics research

Odile Carrette a , Pierre R Burkhard a, b , Jean-Charles Sanchez a , Denis F Hochstrasser a, c, d
Keywords: 2D Electrophoresis, Absorption, Alkylations, Carcinogens, Clinical, Clinical Chemistry, Deposition, Detergents, Electrophoresis, Gel electrophoresis, High performance liquid chromatography, Immobilization, Isoelectric focusing, Mutagens, Neurology, PAGE, Polymerization reactions, Precipitation, Protein assay, Protein electrophoresis, Proteomics, Reductions, Respiratory, Sample preparations, Separation, Size-exclusion chromatography, Teratogens

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Peer-Reviewed Papers
15

References

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