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31742 Sigma-Aldrich

Levamisol hydrochloride

VETRANAL, analytical standard

Synonym: (−)-Tetramisole hydrochloride, (S)-(−)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole hydrochloride, L(−)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole hydrochloride, Levamisole hydrochloride

  • CAS Number 16595-80-5

  • Empirical Formula (Hill Notation) C11H12N2S · HCl

  • Molecular Weight 240.75

  •  Beilstein Registry Number 4358988

  •  EC Number 240-654-6

  •  MDL number MFCD00012675

  •  PubChem Substance ID 329753914

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Properties

Related Categories Analytical Standards, Analytical/Chromatography, Antibiotics, Antibiotics A to Z, Antibiotics G-M,
grade   analytical standard
InChI Key   LAZPBGZRMVRFKY-HNCPQSOCSA-N
product line   VETRANAL
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
mp   228-230 °C
format   neat

Description

Biochem/physiol Actions

Shows both immunostimulant and immunosuppressant effects, depending on several controllable factors. Very effective in treatment of ascariasis (hookworm infestation). Useful in chemotherapy of colorectal cancers, possibly due to its stimulation of IL-1 production and direct activation of macrophages.

Application

Levamisol hydrochloride may have been used as antibiotic standard in ultra-high-pressure liquid chromatography–tandem mass spectrometry for determination of veterinary drug residues from milk samples.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Levamisol hydrochloride is an anthelmintic drug which possesses immunomodulatory and anticancer properties. It is a white crystalline compound which is stable in acid aqueous media, whereas it hydrolyzes in alkaline/neutral solutions.

Legal Information

VETRANAL is a trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3
RTECS 
NJ5960000
Protocols & Articles

Articles

HPLC Analysis of Tetramisole Enantiomers and Related Compounds on Astec® CYCLOBOND® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tetramisole Enantiomers and Related Compounds on Astec® CYCLOBOND® I 2000 DMP
Keywords: Chromatography, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Metabolites, Pharmaceutical, Separation, Solvents

HPLC Analysis of Tetramisole Enantiomers on Astec® CYCLOBOND® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of Tetramisole Enantiomers on Astec® CYCLOBOND® I 2000 DMP
Keywords: Chromatography, High performance liquid chromatography, Mass spectrometry, Pharmaceutical

HPLC Chiral Analysis of Levamisole on Astec® Cyclobond® I 2000 DMP

From our library of Articles, Sigma-Aldrich presents HPLC Chiral Analysis of Levamisole on Astec® Cyclobond® I 2000 DMP
Keywords: Chromatography, High performance liquid chromatography

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