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48975 Sigma-Aldrich

Gliotoxin from Gliocladium fimbriatum

≥98.0% (TLC)

  • CAS Number 67-99-2

  • Empirical Formula (Hill Notation) C13H14N2O4S2

  • Molecular Weight 326.39

  •  Beilstein Registry Number 50675

  •  MDL number MFCD00058534

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Properties

InChI Key   FIVPIPIDMRVLAY-RBJBARPLSA-N
assay   ≥98.0% (TLC)
solubility   chloroform: 10 mg/mL, clear, colorless
Mode of action   DNA synthesis | interferes
  enzyme | inhibits
antibiotic activity spectrum   viruses
storage temp.   2-8°C

Description

Application

Noncompetitive inhibitor of the chymotrypsin-like activity of the 20S proteasome in vitro.

Other Notes

Antiphagocytic and immunomodulating agent which acts by blocking membrane thiol groups

General description

Chemical structure: epipolythiodioxopiperazine

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3462 6.1 / PGIII
WGK Germany 
3
RTECS 
KB4725000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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G9893 Gliotoxin from Gliocladium fimbriatum

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