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A5099 SAFC

N-Acetyl-L-cysteine

PharmaGrade, Ajinomoto, Manufactured under appropriate GMP controls for pharma or biopharmaceutical production, suitable for cell culture

Synonym: LNAC, NAC

  • CAS Number 616-91-1

  • Linear Formula HSCH2CH(NHCOCH3)CO2H

  • Molecular Weight 163.19

  •  Beilstein/REAXYS Number 1724426

  •  EC Number 210-498-3

  •  MDL number MFCD00004880

  •  PubChem Substance ID 24890942

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Properties

Related Categories A - H, Amino Acids, Amino acids, Analytical/Chromatography, Biochemicals and Reagents,
biological source   non-animal source
grade   Non-Compendial
product line   PharmaGrade
assay   ≥98.5%
form   crystalline powder
mfr. no.   Ajinomoto
application(s)   cell culture | mammalian: suitable
impurities   endotoxin, heavy metals, trace metals, tested
mp   106-108 °C (lit.)
solubility   H2O: ≥10 mg/mL
Featured Industry   Pharmaceutical (small molecule)
foreign activity   cytotoxicity, tested
SMILES string   CC(=O)N[C@@H](CS)C(O)=O
InChI   1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChI key   PWKSKIMOESPYIA-BYPYZUCNSA-N

Description

General description

PharmaGrade products are manufactured under appropriate controls for use as a raw material in pharma or biopharmaceutical production. For more information on the PharmaGrade Program, visit sigma-aldrich.com/safc-pharmagrade.

Application

This product has been discontinued. no need to update

Biochem/physiol Actions

Antioxidant and mucolytic agent. Increases cellular pools of free radical scavengers. Reported to prevent apoptosis in neuronal cells but induce apoptosis in smooth muscle cells. Inhibits HIV replication. May serve as a substrate for microsomal glutathione transferase.

Linkage

To request the Enhanced Quality Product Documentation for this product, submit a PharmaGrade Product Information Request Form. Please note that access to the Enhanced Quality Product Documentation for this product requires a confidentiality disclosure agreement.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
HA1660000

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Dietary Antioxidants

Antioxidants protect biological systems from oxidative damage produced by oxygen-containing free radicals and from redoxactive transition metal ions such as iron, copper, and cadmium.1 During the oxi...
Biofiles Volume 2 Article 2
Keywords: Adhesion, Anti-inflammatory agents, Applications, Cancer, Cardiovascular, Catalysis, Diabetes, Diseases, Gene expression, Metabolism, Neurodegenerative Diseases, Peroxidations, Phosphorylations, Prebiotics, Probiotics, Reductions, Transcription, Transduction, Vitamins

HPLC Analysis of 15N-Acetylcysteine Enantiomers on Astec® (R,R) P-CAP™

From our library of Articles, Sigma-Aldrich presents HPLC Analysis of 15N-Acetylcysteine Enantiomers on Astec® (R,R) P-CAP™
Keywords: Chromatography, High performance liquid chromatography

Peer-Reviewed Papers
15

References

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