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A9797 Sigma-Aldrich

Ambroxol hydrochloride

analytical standard

Synonym: 2-Amino-3,5-dibromo-N-(trans-4-hydroxycyclohexyl)benzylamine

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Properties

Related Categories Additional Drugs, Additional Standards, Analytical Standards, Analytical/Chromatography, Bromhexine Metabolite,
grade   analytical standard
InChI Key   QNVKOSLOVOTXKF-PFWPSKEQSA-N
form   neat
shelf life   limited shelf life, expiry date on the label
application(s)   HPLC: suitable
  gas chromatography (GC): suitable
format   neat
storage temp.   2-8°C

Description

Biochem/physiol Actions

Metabolite of bromhexine.
A Nav1.8-preferring sodium channel blocker

Application

Ambroxol hydrochloride standard may be used as a reference standard in the determination of ambroxol hydrochloride in pharmaceutical preparations using reversed-phase sequential injection chromatography (RP-SIC) and reversed-phase high performance liquid chromatography (RP-HPLC).

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

General description

Ambroxol hydrochloride is a mucolytic expectorant and a metabolite of bromhexine. It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
GV8425000

Documents

Certificate of Analysis

Certificate of Origin


Milli-Q® Water Purification Solutions
Protocols & Articles
Peer-Reviewed Papers
15

References

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