D6750 Sigma-Aldrich

Sodium deoxycholate

≥97% (titration)

Synonym: 3α,12α-Dihydroxy-5β-cholanic acid sodium salt, 7-Deoxycholic acid sodium salt, Desoxycholic acid sodium salt

  • CAS Number 302-95-4

  • Empirical Formula (Hill Notation) C24H39NaO4

  • Molecular Weight 414.55

  •  Beilstein/REAXYS Number 3581950

  •  EC Number 206-132-7

  •  MDL number MFCD00064139

  •  PubChem Substance ID 24894044

  •  NACRES NA.21



Related Categories Anionic Detergents, Antigen-Vaccine Preparation, Bile Salts, Bile acids and Derivatives, Biochemicals and Reagents,
Quality Level   200
biological source   bovine bile
description   anionic
assay   ≥97% (titration)
form   powder
mol wt   micellar avg mol wt 1200-5000
aggregation number   3-12
CMC   2-6 mM (20-25°C)
HLB   16
functional group   carboxylic acid
shipped in   ambient
storage temp.   room temp
SMILES string   [Na+].[H][C@]12CC[C@@]3([H])[C@]4([H])CC[C@H]([C@H](C)CCC([O-])=O)[C@@]4(C)[C@@H](O)C[C@]3([H])[C@@]1(C)CC[C@@H](O)C2
InChI   1S/C24H40O4.Na/c1-14(4-9-22(27)28)18-7-8-19-17-6-5-15-12-16(25)10-11-23(15,2)20(17)13-21(26)24(18,19)3;/h14-21,25-26H,4-13H2,1-3H3,(H,27,28);/q;+1/p-1/t14-,15-,16-,17+,18-,19+,20+,21+,23+,24-;/m1./s1


General description

Sodium deoxycholate is a bile salt and an ionic detergent. Bile salts work along with lipids/fats/cholesterol and form mixed micelles in the intestine. These micelles help in fat digestion and absorption through the intestinal wall.


Sodium deoxycholate has been used in the lysis buffer prepared for brown adipose tissue. It has been used in the decellularization of aortic valvular conduit.


10, 25, 100, 500 g in poly bottle

Biochem/physiol Actions

Solubilizes fats for absorption in the intestines.

Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
NONH for all modes of transport
WGK Germany 
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable


Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles


Bile Acids

The liver excretes excess cholesterol in the form of bile acids. Bile acids serve two purposes: to remove unwanted cholesterol from the body and to aid in lipid digestion in the intestine. Bile acids...
BioFiles 2007, 2.7, 17.
Keywords: Absorption, Digestions, Transcription

Bile Salts and Bile Salt Hydrolase

Several Lactobacillus and Bifidobacterium probiotic strains exhibit bile salt hydrolase (BSH) activity and are suspected to play a role in combating the negative effects of bile via detoxification of...
Chloe McClanahan
Biofiles Edition 6.2
Keywords: Detoxification, Probiotics, Thin layer chromatography, Titrations

Manufacturing, Characterization and Use of Single Walled Carbon Nanotubes

Carbon nanotubes are materials that possess remarkable properties and offer extraordinary possibilities. This article gives a brief overview of the physico-chemical nature and characterization of sin...
Richard Jansen, Philip Wallis
Material Matters 2009, 4.1, 23.
Keywords: Absorption, Catalysis, Centrifugation, Chemical vapor deposition, Diffraction, Indicators, Infrared spectroscopy, Nanotechnology, Nanotubes, Oxidations, Purification, Raman spectroscopy, Semiconductor, Solar cells, Sonication, Spectroscopy, Ultraviolet-Visible spectroscopy, X-Ray diffraction

Probiotics and Human Health

At the beginning of the 20th century, probiotics were thought to have a beneficial effect to the host by improving the intestinal microbial balance. Through his studies and observations, the Russian ...
Chloe McClanahan
BioFiles Edition 6.2
Keywords: AGE, Absorption, Adhesion, Amplification, Anaerobic, Antimicrobials, Cancer, Carcinogens, Cell proliferation, Chromatography, Coagulation, Detoxification, Diagnostic, Diseases, Enzyme activity, Fermentation, Gas chromatography, Gastrointestinal, High performance liquid chromatography, Inflammation, Magnetic resonance spectroscopy, Metabolism, Metabolites, Molecular biology, Nucleic acid hybridization, PAGE, Pharmaceutical, Phosphorylations, Polymerase chain reaction, Prebiotics, Probiotics, Reductions, Respiratory, Sequencing, Thin layer chromatography, Titrations


Single-Walled Carbon Nanotubes: Exfoliation and Debundling Procedure

The dispersibility and bundle defoliation of single-walled carbon nanotubes (SWCNTs), which can be applied to materials produced by the CoMoCAT® process, have been extensively investigated by SouthWe...
Keywords: Absorption, Adsorption, Centrifugation, Nanotubes, Sonication

Peer-Reviewed Papers


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