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03907 Sigma

Tioconazole

97%

Synonym: 1-[2-[(2-Chloro-3-thienyl)methoxy]-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole, Thioconazole

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Properties

Related Categories Antibiotics, Antibiotics A to Z, Antibiotics T-Z, Antifungal, Biochemicals and Reagents,
InChI Key   QXHHHPZILQDDPS-UHFFFAOYSA-N
assay   ≥96.5% (HPLC)
  96.5-103.5% (NT)
  97%
form   powder
color   white to off-white
Mode of action   cell membrane | interferes
antibiotic activity spectrum   fungi
  yeast

Description

Packaging

10G

Application

Tioconazole was used to study the synergistic mechanisms of antifungals on Candida albicans as well as significant drug-drug interactions in vivo.

Biochem/physiol Actions

Tioconazole is an antifungal medication of the imidazole class used to treat infections caused by fungus and yeast.It is more active than fluconazole or voriconazole against Candida glabrata mutant strains. It acts by membrane disruption and loss of intracellular ATP.

General description

Chemical structure: pyrimidine

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. 03907.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NI4480000
Protocols & Articles
Peer-Reviewed Papers
15

References

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