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91590C SAFC

LONG® R3 IGF-I solution human

recombinant, expressed in E. coli, liquid

  •  NACRES NA.77

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Properties

Related Categories CHO Platform, Cell Culture, Serum-free Media, Supplements
recombinant   expressed in E. coli
form   liquid
storage temp.   2-8°C

Description

General description

LONG® R3 IGF-I is a recombinant analog of human insulin-like growth factor-I (IGF-I) that has been specifically engineered for the enhancement of cell culture performance. It is more biologically potent in vitro than either insulin or native IGF-I and has been shown to significantly increase recombinant protein production. It is ideal for both research and large-scale culture systems utilizing serum-free or low-level serum applications. LONG R3 IGF-I provides equivalent or better performance to recombinant insulin depending on the cell line and clone.
LONG R3 IGF-I is produced in an Escherichia coli expression system without the use of animal-derived components.

Application

LONG R3 IGF-I has been used with numerous cell types including CHO, vaccine-producing cell lines, fibroblasts and stem cells. All cell types that have a growth response to insulin in cell culture have the potential to respond to LONG R3 IGF-I.
LONG® R3 IGF-I solution human has been used to induce myotube hypertrophy in cells.

Linkage

For more information about LONG®R3 IGF-I, please visit the LONG®R3 IGF-I web page

Other Notes

Please contact your local SAFC sales representative to order.

Legal Information

Available in USA, Canada, and Europe. Please check with your local supplier regarding availability and restrictions in other countries.

LONG is a registered trademark of Repligen Sweden AB

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis (COA)

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Protocols & Articles

Articles

LONG®R3IGF-I - GMP Growth Factor Additive for Cell Culture Manufacturing

It is often hard to maintain or improve productivity in serum or animal-free formulations. Many biopharmaceutical manufacturers are trying to eliminate animal-containing raw materials, or move toward...

Keywords: Apoptosis, Cell culture, Cell proliferation, Clinical, Culture media, Diabetes, Fermentation, Gene expression, Growth factors, Infrared spectroscopy, Substitutions, Transduction

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LONG®R3IGF-I

Improving productivity, reducing complexity and mitigating risk is the goal of every Process Development Scientist. For over 20 years, IGF-I has been a proven cGMP cell culture growth factor used LON...
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Peer-Reviewed Papers
15

References

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