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A6625 Sigma

Acetylcholine chloride

≥99% (TLC)

Synonym: ACh

  • CAS Number 60-31-1

  • Linear Formula (CH3)3N+CH2CH2OCOCH3Cl-

  • Molecular Weight 181.66

  •  Beilstein Registry Number 3571875

  •  EC Number 200-468-8

  •  MDL number MFCD00011698

  •  PubChem Substance ID 57653875

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Description

Caution

Very hygroscopic

Packaging

10 mg in glass bottle

25, 100, 500 g in glass bottle

Application

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Biochem/physiol Actions

Acetylcholine chloride, injected at 20 mg/kg body weight, reduces mortality and plasma proinflammatory cytokines in mice with experimentally-induced sepsis . The cholinergicanti-infl ammatory mechanism is probably mediated by interaction of acetylcholine with α7n cholinoreceptor on monocytes, macrophages, and neutrophils, which decreases the levels of proinflammatory cytokines such as TNF-α, IL-1β, and IL-6.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
FZ9800000
Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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