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A6850 Sigma-Aldrich

Azelaoyl PAF

10 mg/mL in ethanol

Synonym: 1-O-Hexadecyl-2-O-(9-carboxyoctanoyl)-sn-glyceryl-3-phosphocholine, 1-O-Hexadecyl-2-azelaoyl-sn-glycero-3-phosphocholine, hexadecyl azelaoyl phosphatidylcholine

  • Empirical Formula (Hill Notation) C33H66NO9P

  • Molecular Weight 651.85

  •  EC Number 200-578-6

  •  MDL number MFCD03412018

  •  PubChem Substance ID 329770906

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Properties

Related Categories AN-AZ, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   200
form   liquid
concentration   10 mg/mL in ethanol
shipped in   wet ice
storage temp.   −20°C
SMILES string   [O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCCC(O)=O)=O)COCCCCCCCCCCCCCCCC)=O
InChI   1S/C33H66NO9P/c1-5-6-7-8-9-10-11-12-13-14-15-16-20-23-27-40-29-31(30-42-44(38,39)41-28-26-34(2,3)4)43-33(37)25-22-19-17-18-21-24-32(35)36/h31H,5-30H2,1-4H3,(H-,35,36,38,39)/t31-/m1/s1
InChI key   ZDFOCDTXDPKJKA-WJOKGBTCSA-N

Description

Application

Azelaoyl PAF is a potent PPARγ agonist. Azelaoyl PAF has been used to investigate whether peroxisome proliferator-activated receptors gamma agonists could play a role in the treatment of Friedreich′s ataxia, a neurodegenerative disease due to frataxin deficiency.

Biochem/physiol Actions

Potent PPARγ agonist.

Features and Benefits

This compound is featured on the Nuclear Receptors (PPARs) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
RIDADR 
UN1170 - class 3 - PG 2 - Ethanol
WGK Germany 
2
Flash Point(F) 
57.2 °F
Flash Point(C) 
14 °C

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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