• USA Home
  • A7611 - Azelastine hydrochloride

EMAIL THIS PAGE TO A FRIEND
A7611 Sigma

Azelastine hydrochloride

≥98% (HPLC)

Synonym: 4-[(4-chlorophenyl)methyl]-2-(1-methylazepan-4-yl)phthalazin-1-one hydrochloride, Astelin, Optivar

  • CAS Number 79307-93-0

  • Empirical Formula (Hill Notation) C22H24ClN3O · HCl

  • Molecular Weight 418.36

  •  MDL number MFCD00242783

  •  PubChem Substance ID 329770938

Purchase

Properties

Related Categories AN-AZ, Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules,
InChI Key   YEJAJYAHJQIWNU-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   white to off-white
solubility   DMSO: >10 mg/mL
originator   Wallace
storage temp.   −20°C

Description

Biochem/physiol Actions

H1 histamine receptor antagonist; NF-kB activator.

Packaging

10, 50 mg in glass bottle

Application

Azelastine hydrochloride is a H1 histamine receptor antagonist and NF-kB activator. Azelastine hydrochloride has been used in a study to investigate the potential of polymeric microspheres for treatment of allergic conjunctivitis.

Features and Benefits

This compound is featured on the Histamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Wallace. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport

Documents

Certificate of Analysis


Discover your Target

Making Headway
Protocols & Articles

Articles

Histamine Receptors

The biogenic amine histamine plays an important role in a variety of pathophysiological conditions. In peripheral tissues, histamine is mainly stored in mast cells and basophils. In allergic conditio...
Keywords: Alzheimer Disease, Atomic absorption spectroscopy, Cardiovascular, Clinical, Diseases, Gene expression, Inflammation, Ligands, Neurotransmitters, Obesity, Transduction

Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?