EMAIL THIS PAGE TO A FRIEND
A9477 Sigma

Aldosterone

≥95% (HPLC)

Synonym: 11β,21-Dihydroxy-3,20-dioxo-4-pregnen-18-al, 11β,21-Dihydroxypregn-4-ene-3,18,20-trione, 18-Aldocorticosterone, Reichstein X

  • CAS Number 52-39-1

  • Empirical Formula (Hill Notation) C21H28O5

  • Molecular Weight 360.44

  •  Beilstein Registry Number 3224996

  •  EC Number 200-139-9

  •  MDL number MFCD00051136

  •  PubChem Substance ID 24891458

Purchase

Description

Application

The d-isomer of aldosterone is considered to be the biologically active isomer.

Biochem/physiol Actions

Biologically active aldosterone isomer; a mineralocorticoid produced by the adrenal cortex that induces urinary excretion of K+ and renal reabsorption of Na+.

Other Notes

Exists as an equilibrium mixture of the aldehyde and the hemiacetal.

Packaging

100 mg in poly bottle

5, 25 mg in glass insert

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
TU4523000

Documents

Certificate of Analysis

Certificate of Origin

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis.
How do I get lot-specific information or a Certificate of Analysis?
The lot specific COA document can be found by entering the lot number above under the "Documents" section.
How do I find price and availability?
There are several ways to find pricing and availability for our products.Once you log onto our website, you will find the price and availability displayed on the product detail page.You can contact any of our Customer Sales and Service offices to receive a quote. USA customers: 1-800-325-3010 orview local office numbers.
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.
IsProduct A9477, Aldosterone,the d- or l- isomer?
The A9477 is the d-Aldosterone (per our supplier), which is considered to be the biologically active isomer.
How do I make a stock solution of Product A9477, Aldosterone?
To prepare a 100 μg/ml stock solution, add 5 ml of absolute ethanol to 5 mg, gently swirl to dissolve, then add 45 ml sterile medium. Freeze the stock in working aliquots, but avoid repeated freeze/thaw cycles.
Is Product A9477, Aldosterone, tested for solubility?
Yes, A9477 is tested for solubility using 20mg/ml in chloroform. For biological applications, you can solubilize aldosterone in ethanol to at least 1 mg/mL. Please refer to literature references for further solubility information.
What is the difference between Aldosterone Products A9477 and 05521?
The main differences between A9477 and 05521 are the assays performed on the products. The assay results are lot specific and can be viewed on the Certificate of Analysis.
My question is not addressed here, how can I contact Technical Service for assistance?
Ask a Scientist here.
Show more questions

Meet Synthia - Retrosynthesis Sofware

Discover your Target
Protocols & Articles

Articles

LC/MS/MS Analysis of Steroid Hormones in Plasma on Ascentis® Express C18 after Sample Prep using HybridSPE®-Phospholipid

From our library of Articles, Sigma-Aldrich presents LC/MS/MS Analysis of Steroid Hormones in Plasma on Ascentis® Express C18 after Sample Prep using HybridSPE®-Phospholipid
Keywords: Anticonvulsants, Chromatography, Clinical, High performance liquid chromatography, Hormones, Liquid chromatography mass spectrometry, Mass spectrometry, Pharmaceutical, Precipitation, Separation, Solid phase extractions, Solvents

Peer-Reviewed Papers
15

References

Related Products

related product

Product #

Description

Add to Cart

706035 Aldosterone-2,2,4,6,6,21,21-d7 , ≥98 atom % D (based on d7), ≥98% (CP)

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?