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A9611 Sigma

Atipamezole

≥98% (HPLC)

Synonym: 4-(2-Ethyl-2,3-dihydro-1H-inden-2-yl)-1H-Imidazole, Antisedan, MPV 1248

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Properties

Related Categories AN-AZ, Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   HSWPZIDYAHLZDD-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
color   white to brown
solubility   DMSO: ≥30 mg/mL
originator   Pfizer
storage temp.   room temp

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Atipamezole is a selective α2 adrenergic blocker. Atipamezole is more potent than yohimbine; it is very selective for α2 adrenergic vs α1 sites, but not selelctive for α2 subtypes.

Features and Benefits

This compound is a featured product for Neuroscience research. Click here to discover more featured Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound is featured on the α2-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Pfizer. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Discover your Target

Making Headway
Protocols & Articles

Articles

Discover Bioactive Small Molecules for Neuroscience

The nervous system, comprised of the brain and spinal cord (central nervous system, or CNS) and network of nerves that connects the CNS to the rest of the body (peripheral nervous system, or PNS) is ...
Keywords: Bioactive small molecules, Central Nervous System, Diseases, Metabolism, Neurodegenerative Diseases, Neuroscience, Neurotransmission, Neurotransmitters

α2-Adrenoceptors

α2-Adrenoceptors are widely distributed and are activated by norepinephrine (A7257, A0937), released from sympathetic nerve terminals or by epinephrine (E4250, E4375), released from the adrenal medul...
Keywords: Analgesics, Atomic absorption spectroscopy, Cardiovascular, Eliminations, Gene expression, Genetic, Neurotransmission, Neurotransmitters, Transduction

Peer-Reviewed Papers
15

References

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