• USA Home
  • B8776 - Botulinum Toxin A from Clostridium botulinum

EMAIL THIS PAGE TO A FRIEND
B8776 Sigma

Botulinum Toxin A from Clostridium botulinum

lyophilized powder

Purchase

Properties

form   lyophilized powder
shipped in   dry ice
storage temp.   −20°C

Description

Other Notes

Handle the toxin gently. Do not vortex. Use sufficient volume of buffer to wash down the walls and stopper. Read all handling information found on SDS prior to reconstitution.

Preparation Note

When toxin is used for in vitro studies, it is preincubated in a buffer containing 5 mM dithiothreitol for 30 minutes in order to reduce and thereby activate the toxin.

Reconstitution

Reconstitute each 100 μg vial with 100 μL of appropriate buffer. Upon reconstitution, the vial will contain 20 mM HEPES and 1.25% lactose. To insure full recovery of toxin from the vial, include 1 mg/mL BSA in the reconstitution buffer.

Physical form

Lyophilized powder containing 20 mM HEPES and 1.25% lactose when reconstituted with the volume of water or buffer indicated on the Certifcate of Analysis.

Biochem/physiol Actions

Neurotoxin that inhibits release of catecholamines from adrenal medulla; blocks release of acetylcholine at neuromuscular junctions.

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3172 6.1 / PGI
WGK Germany 
2

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?