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C2278 Sigma-Aldrich

CAPSO

≥99% anhydrous basis (titration)

Synonym: 3-(Cyclohexylamino)-2-hydroxy-1-propanesulfonic acid, CAPSO Free Acid

  • CAS Number 73463-39-5

  • Empirical Formula (Hill Notation) C9H19NO4S

  • Molecular Weight 237.32

  •  Beilstein/REAXYS Number 5939234

  •  MDL number MFCD00041778

  •  PubChem Substance ID 24892483

  •  NACRES NA.25

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Properties

Related Categories Biochemicals and Reagents, Biological Buffers, Buffers A to Z, Good’s Buffers
Quality Level   200
assay   ≥99% anhydrous basis (titration)
form   crystalline powder
pH   2.5-4.0
useful pH range   8.9 - 10.3
pKa (25 °C)   9.6
solubility   water: 0.111 g/mL, clear, colorless
Featured Industry   Diagnostic Assay Manufacturing
SMILES string   OC(CNC1CCCCC1)CS(O)(=O)=O
InChI   1S/C9H19NO4S/c11-9(7-15(12,13)14)6-10-8-4-2-1-3-5-8/h8-11H,1-7H2,(H,12,13,14)
InChI key   INEWUCPYEUEQTN-UHFFFAOYSA-N

Description

General description

CAPSO is a useful secondary standard buffer. Second dissociation constant pK2 value of CAPSO has been measured. Useful pH range for CAPSO is 8.9 - 10.3.

Application

CAPSO was used as biological buffer in the following studies:
• To maintain pH 9 during water leach test for the analysis of high-carbon coal fly ash-soil mixtures.
• Chemiluminescent in situ hybridization using soybean peroxidase-labeled peptide nucleic acid (PNA) probes. I
• Preparation of planar bilayer lipid membranes.
It may be employed as buffer for the electrophoretic analyses in non-denaturing gels, to investigate macromolecular self-association of ADP-ribosyltransferase protein in solution.

Packaging

1 kg in poly bottle

25, 100, 500 g in poly bottle

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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pHast Pack
Protocols & Articles

Articles

UHPLC Analysis NIST mAb Variants on Proteomix SCX-NP5: Comparing Salt and pH Gradients

From our library of Articles, Sigma-Aldrich presents UHPLC Analysis NIST mAb Variants on Proteomix SCX-NP5: Comparing Salt and pH Gradients
Keywords: Chromatography, Ion Exchange, Separation

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Peer-Reviewed Papers
15

References

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