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C2485 Sigma-Aldrich

β-Cyclodextrin polymer

powder

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Properties

Related Categories Biochemicals and Reagents, Carbohydrates, Carbohydrates A to Z, Carbohydrates A-C, Chelation/Complexation Compounds,
Quality Level   100
biological source   synthetic
form   powder
mol wt   average mol wt 2,000 --300,000 Da
composition   Cyclodextrin content, 60% iodometric
solubility   H2O: soluble 100mg plus 1 mL, clear, colorless to light yellow
storage temp.   2-8°C

Description

General description

Cyclodextrins (CD) are cyclic oligosaccharides composed of D-glucose units connected via α(1,4) glycosidic bonds. Common cyclodextrins contain six (α-CD); seven (β-CD) or eight (gamma-CD) D-glucose units. Cyclodextrins are sometimes derivatized through esterification at positions two, three and/or six.

Application

Beta-cyclodextrin (β-Cyclodextrin) may be used in the development of biocompatible drug delivery vehicles and membrane constructs to improve compound solubility in aqueous environments. β-cyclodextrin polymer and its ester derivatives are used for the development and construction of biomaterials such as hydrogels, nanoassemblies and biomatricies. β-cyclodextrin may be used for the development of biosensors.

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

Applications of Glucose Polymers in the Synthesis of Diagnostic and Drug Delivery Nanoparticles

Colorado Center for Nanomedicine and Nanosafety, Translational Bio-Nanosciences Laboratory, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of...
Keywords: Absorption, Agriculture, Biomaterials, Building blocks, Cancer, Chromatography, Clinical, Column chromatography, Degradations, Diagnostic, Dialysis, Environmental, High performance liquid chromatography, Inflammation, Ligands, Magnetic resonance imaging, Nucleic acid hybridization, Oxidations, PEGylations, Pharmaceutical, Polymerization reactions, Positron Emission Tomography, Purification, Reductions

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Lab Chemicals

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Keywords: Gas chromatography, Infrared spectroscopy, Sublimation, Thin layer chromatography

Peer-Reviewed Papers
15

References

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