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C3506 Sigma-Aldrich

Cytosine

≥99%

Synonym: 4-Amino-2-hydroxypyrimidine, 4-Aminopyrimidin-2-(1H)-one

  • CAS Number 71-30-7

  • Empirical Formula (Hill Notation) C4H5N3O

  • Molecular Weight 111.10

  •  Beilstein/REAXYS Number 2637

  •  EC Number 200-749-5

  •  MDL number MFCD00006034

  •  PubChem Substance ID 24892620

  •  NACRES NA.51

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Properties

Related Categories Biochemicals and Reagents, Nucleosides, Nucleosides, Nucleotides, Oligonucleotides More...
assay   ≥99%
mp   >300 °C (lit.)
SMILES string   NC1=NC(=O)NC=C1
InChI   1S/C4H5N3O/c5-3-1-2-6-4(8)7-3/h1-2H,(H3,5,6,7,8)
InChI key   OPTASPLRGRRNAP-UHFFFAOYSA-N

Description

Application

Cytosine has been used:
• for the preparation of nucleobase solutions
• as a standard for high-performance liquid chromatography (HPLC)
• for the estimation of global methylation rate
• for nucleoside 5′-triphosphate (NTP) synthesis
• purification

Packaging

1, 5, 10, 25, 100 g in poly bottle

Biochem/physiol Actions

Cytosine (C) is one of the four main bases found in DNA and RNA, along with adenine, guanine, and thymine (uracil in RNA).

Cytosine is a pyrimidine, which forms three hydrogen bonds to base pair with guanine. It forms a nucleotide cytidine, that is phosphorylated to cytidine 5′ monophosphate (CMP), cytidine 5′ diphosphate (CDP) and cytidine 5′ triphosphate (CTP).

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
UW7350150

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

Articles

MSMLS Online Plate Map

Metabolite descriptors included with the software download upon purchase of the product include: Name, Parent CID, molecular formula, molecular weight, CAS, ChEBI, HMDB ID, PubChem Compound and Subst...
Keywords: Mass spectrometry, Metabolites

Peer-Reviewed Papers
15

References

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