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D027 Sigma-Aldrich

R(−)-Propylnorapomorphine hydrochloride

solid

Synonym: R(−)-10,11-Dihydroxy-N-n-propylnoraporphine hydrochloride, R(−)-NPA hydrochloride

  • CAS Number 18426-20-5

  • Empirical Formula (Hill Notation) C19H21NO2 · HCl

  • Molecular Weight 331.84

  •  MDL number MFCD00069239

  •  PubChem Substance ID 24277901

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Properties

Related Categories Agonists, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
InChI Key   PCOQOGIDTIFQAM-XFULWGLBSA-N
form   solid
optical activity   [α]22/D −70.3°, c = 0.17 in methanol(lit.)
color   off-white
solubility   0.1 M HCl: 5-10 mg/mL (Solutions should be freshly prepared)
  methanol: 5-10 mg/mL (Solutions should be freshly prepared)
  H2O: moderately soluble (dissolve in oxygen-free boiled water containing 0.1% sodium metabisulfite or other antioxidants. Solutions should be freshly prepared.)
  alcohol: moderately soluble (Solutions should be freshly prepared.)
  aqueous base: insoluble
storage temp.   2-8°C
Gene Information   human ... DRD2(1813)

Description

Biochem/physiol Actions

Highly potent and selective D2 dopamine receptor agonist.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Caution

Subject to rapid oxidation.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

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Certificate of Origin

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Making Headway

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Protocols & Articles
Peer-Reviewed Papers
15

References

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