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D7071 Sigma

Dapoxetine hydrochloride

≥98% (HPLC)

Synonym: (S)-N,N-dimethyl-1-phenyl-3-(1-naphthalenyloxy)propanamine hydrochloride, S-(+)-N,N-dimethyl-a-[2-(naphthalenyloxy)ethyl] benzenemethanamine hydrochloride, LY-210448 hydrochloride

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, D-DIF,
InChI Key   IHWDIQRWYNMKFM-BDQAORGHSA-N
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D +125 to +135°, c = 1 in methanol
color   white
solubility   DMSO: ≥20 mg/mL
originator   Eli Lilly
storage temp.   room temp

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Potent Selective serotonin reuptake inhibitor (SSRI); used in treatment of premature ejaculation

Features and Benefits

This compound is featured on the Biogenic Amine Transporters page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis


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Making Headway
Protocols & Articles

Articles

Biogenic Amine Transporters

Following vesicular release, the biogenic amine neurotransmitters, norepinephrine (A7257), dopamine (H8502) and serotonin (H9523), are removed from the extracellular space by selective and pharmacolo...
Keywords: Anti-depressants, Atomic absorption spectroscopy, Clinical, Cloning, Gene expression, Ligands, Neurotransmission, Neurotransmitters, Parkinson Disease, Phosphorylations, Schizophrenia

Peer-Reviewed Papers
15

References

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