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D9175 Sigma-Aldrich

Dantrolene sodium salt

Synonym: 1-[(5-­(p-Nitro­phenyl)­fur­furyl­idene)­amino]­hydan­toin sodium salt

  • CAS Number 14663-23-1

  • Empirical Formula (Hill Notation) C14H9N4NaO5

  • Molecular Weight 336.23

  •  MDL number MFCD00079130

  •  PubChem Substance ID 24278823

  •  NACRES NA.77

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience,
Quality Level   200
originator   JHP Pharmaceuticals
SMILES string   [Na+].[H]\C(=N/N1CC(=O)N=C1[O-])c2ccc(o2)-c3ccc(cc3)[N+]([O-])=O
InChI   1S/C14H10N4O5.Na/c19-13-8-17(14(20)16-13)15-7-11-5-6-12(23-11)9-1-3-10(4-2-9)18(21)22;/h1-7H,8H2,(H,16,19,20);/q;+1/p-1/b15-7+;
InChI key   KSRLIXGNPXAZHD-HAZZGOGXSA-M

Description

Packaging

1 g in glass bottle

100, 250 mg in glass bottle

Biochem/physiol Actions

Inhibitor of Ca2+ release from sarcoplasmic reticulum; muscle relaxant.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound is featured on the InsP3/Ryanodine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by JHP Pharmaceuticals. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

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Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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