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E6511 Sigma-Aldrich

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate

BioReagent, suitable for cell culture, 99.0-102.0%

Synonym: EDTA tetrasodium salt, Edathamil, Tetrasodium ethylenediaminetetraacetate dihydrate

  • CAS Number 10378-23-1

  • Linear Formula (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · 2H2O

  • Molecular Weight 416.20

  •  Beilstein/REAXYS Number 3861753

  •  EC Number 200-573-9

  •  MDL number MFCD00150026

  •  PubChem Substance ID 24894629

  •  NACRES NA.75

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Properties

Related Categories Calcium Signaling Research Tools, Cell Biology, Cell Culture, Cell Dissociation, Cell Signaling and Neuroscience,
product line   BioReagent
assay   99.0-102.0%
form   powder
application(s)   cell culture | mammalian: suitable
solubility   H2O: 160 mg/mL
shipped in   ambient
storage temp.   room temp
SMILES string   O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
InChI   1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
InChI key   KSYNLCYTMRMCGG-UHFFFAOYSA-J

Description

General description

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions. It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production. EDTA is an inhibitor of metalloprotease. It has anticoagulant property.

Application

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:
• as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood
• as a chelator in animal and testicular cell isolation
• as a chelator for the culture of neural stem cells

Used to eliminate enzyme inhibition by traces of heavy metals, and to inhibit enzymes that require divalent cations as cofactors.

Packaging

100, 500 g in poly bottle

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Target organs 
Respiratory Tract
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
2

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles

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Peer-Reviewed Papers
15

References

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