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E8031 Sigma

Esmolol hydrochloride

≥98% (HPLC), solid

Synonym: 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]benzenepropanoic acid methyl ester hydrochloride hydrochloride

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Baxter, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology,
InChI Key   GEKNCWBANDDJJL-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   solid
mp   89.0-90.6 °C
solubility   H2O: 12 mg/mL
originator   Baxter
storage temp.   2-8°C

Description

Biochem/physiol Actions

Esmolol hydrochloride is a ultrashort-acting β1 adrenoceptor antagonist (β1 receptor occupancy = 84.7%).

Packaging

10, 50 mg in glass bottle

Features and Benefits

This compound is featured on the β-Adrenoceptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

This compound was developed by Baxter. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
DA8346000

Documents

Certificate of Analysis


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Making Headway
Protocols & Articles

Articles

Antihypertensive Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, Pharmaceutical, Reductions

β-Adrenoceptors

β-Adrenoceptors are widely distributed, found at both central and peripheral sites, and are activated either via norepinephrine released from sympathetic terminals or via epinephrine (E4250, E4375) r...
Keywords: Antihypertensives, Atomic absorption spectroscopy, Diabetes, Gene expression, Neurotransmitters, Obesity, Reductions, Transduction

Peer-Reviewed Papers
15

References

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