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F7626 Sigma-Aldrich

6-Fluoro-DL-tryptophan

crystalline

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Properties

form   crystalline
mp   280-285 °C (dec.) (lit.)
storage temp.   −20°C
SMILES string   NC(Cc1c[nH]c2cc(F)ccc12)C(O)=O
InChI   1S/C11H11FN2O2/c12-7-1-2-8-6(3-9(13)11(15)16)5-14-10(8)4-7/h1-2,4-5,9,14H,3,13H2,(H,15,16)
InChI key   YMEXGEAJNZRQEH-UHFFFAOYSA-N

Description

Application

6-Fluoro-DL-tryptophan (6-F-TRP), a serotonin (5-HT) synthesis inhibitor, is metabolized in the brain and may be useful for tracing neuronal serotoninergic pools. 6-F-TRP is used as a competitive inhibitor of tryptophan binding to albumin and passage through the blood brain barrier (BBB).

Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable
Protocols & Articles
Peer-Reviewed Papers
15

References

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