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F9677 Sigma

Felodipine

solid

Synonym: 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinecarboxylic acid ethyl methyl ester, Plendil

  • CAS Number 72509-76-3

  • Empirical Formula (Hill Notation) C18H19NO4Cl2

  • Molecular Weight 384.25

  •  MDL number MFCD00868316

  •  PubChem Substance ID 24278449

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Properties

Related Categories Approved Therapeutics/Drug Candidates, AstraZeneca, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Calcium Channel Modulators,
InChI Key   RZTAMFZIAATZDJ-UHFFFAOYSA-N
form   solid
solubility   DMSO: 20 mg/mL
  H2O: insoluble
originator   AstraZeneca
Gene Information   human ... CACNA2D1(781)

Description

Biochem/physiol Actions

L-type calcium channel blocker

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
US7968700

Documents

Certificate of Analysis

Certificate of Origin


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Making Headway
Protocols & Articles

Articles

Antihypertensive Agents

Download BioFiles v7 n5 (3.18 Mb PDF) Back to Pharmaceutical Drugs and Drug Candidates homepage
Sami Barghshoon
BioFiles v7 n5, 2012, 5–20
Keywords: AGE, Antihypertensives, Cardiovascular, Clinical, Diuretics, Pharmaceutical, Reductions

Discover Bioactive Small Molecules for Ion Channels Research

Ion transport across the relatively impermeable lipid bilayer of the cell membrane is accomplished via membrane proteins known as ion channels, pumps and transporters. Ion channels are gated pores an...
Keywords: Biological processes, Cell signaling, Diseases, Hormones, Ligands, Neurotransmitters

Peer-Reviewed Papers
15

References

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