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G0903 Sigma

γ-Glu-Cys

≥80% (HPLC)

Synonym: γ-L-Glutamyl-L-cysteine, des-Gly-glutathione reduced form

  • CAS Number 636-58-8

  • Empirical Formula (Hill Notation) C8H14N2O5S

  • Molecular Weight 250.27

  •  MDL number MFCD00237863

  •  PubChem Substance ID 24895030

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Properties

Related Categories Biochemicals and Reagents, Dipeptides, Dipeptides and Tripeptides, Peptides
InChI Key   RITKHVBHSGLULN-WHFBIAKZSA-N
assay   ≥80% (HPLC)
composition   Peptide content, ≥60% elemental analysis
storage temp.   −20°C

Description

Amino Acid Sequence

Glu-Cys

Physical form

Lyophilized from 0.1% TFA.

Application

γ-Glu-Cys is used to study the active sites and kinetics of glutathione synthetase(s). It has also been used for the extraction and quantification of low molecular weight thiols from Arabidopsis tissues.

Biochem/physiol Actions

γ-L-Glutamyl-L-cysteine (γ-Glu-Cys) is a substrate used for the biosynthesis of L-glutathione by glutathione synthetase(s). γ-Glu-Cys is generated by the cleavage of the Cys-Gly peptide bond of glutathione. It is also essential for the formation of phytochelatins, which are cysteine-rich thiol-reactive peptides.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. G0903.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles
Peer-Reviewed Papers
15

References

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92210 Timestrip Plus 0 °C
06693 Timestrip Plus -20 °C

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