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G1049 Sigma

Poly-L-γ-glutamic acid sodium salt

Synonym: γ-PGA

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Properties

mol wt   mol wt ≥750,000
storage temp.   −20°C

Description

Other Notes

High molecular weight poly-γ-glutamic acid is a polymer of glutamic acid connected by amide linkages between α-amino and γ-carboxylic acid groups. γ-PGA is produced by fermentation in Bacillus species. The subunits are predominantly L-isomer.

Packaging

100 mg in poly bottle

Application

High molecular weight poly-γ-glutamic acid (γPGA) was found to increase levels of NK cell-mediated cytotoxicity and INF-γ secretion in C57BL/6 mice. Biodegradable γ-PGA nanoparticles have been evaluated for use as antigen delivery carriers and delivery of influenza virus hemagglutin (HA) vaccine. Additional life science applications for γ-PGA include uses in biodegradable fibers and nanofiber sheets, hydrogels, and cryoprotectants.

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3

Documents

Certificate of Analysis


Same Products - New Packaging
Protocols & Articles
Peer-Reviewed Papers
15

References

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