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G9548 Sigma

Glabridin

≥98% (HPLC), powder

Synonym: 4-[(3R)-3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl]-1,3-benzenediol, (R)-4-(3,4-Dihydro-8,8-dimethyl-2H,8H-benzo[1,2-b:3,4-b′]dipyran-3-yl)-1,3-benzenediol, Glabridin

  • CAS Number 59870-68-7

  • Empirical Formula (Hill Notation) C20H20O4

  • Molecular Weight 324.37

  •  Beilstein Registry Number 7141956

  •  MDL number MFCD03427694

  •  PubChem Substance ID 329799990

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Properties

Related Categories Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Cell Biology, Flavonoids, Flavonols, and Flavanols, G,
InChI Key   LBQIJVLKGVZRIW-ZDUSSCGKSA-N
assay   ≥98% (HPLC)
form   powder
color   white to light brown
solubility   DMSO: 5 mg/mL, clear (warmed)
storage temp.   room temp

Description

Packaging

5, 25 mg in glass bottle

Biochem/physiol Actions

Glabridin is a bio-available isoflavan isolated from licorice (Glycyrrhiza glabra L.) root extract. Glabridin has been reported to posses varies biological activities including strong antioxidant activity, antioxidant against LDL oxidation, anti-Helicobacter pylori properties, estrogen-like activity and antinephritic and radical scavenging activities. Also it appears to inhibit serotonin re-uptake, melanogenesis, inflammation and cytochrome P450 3A4, 2B6, and 2C9.

Safety & Documentation

Safety Information

Hazard statements 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
Flash Point(F) 
512.6 °F
Flash Point(C) 
267 °C

Documents

Certificate of Analysis


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