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I7003 Sigma

Ibogaine hydrochloride

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Properties

drug control   USDEA Schedule I; regulated under CDSA - not available from Sigma-Aldrich Canada
solubility   H2O: soluble
  methanol: soluble

Description

Preparation Note

Alkaloid isolated from the African shrub, Tabernanthe iboga.

Biochem/physiol Actions

Ibogaine is a central nervous system stimulant and hallucinogen that has been reported to be a σ2 agonist, a noncompetitive NMDA receptor antagonist at the phencyclidine site and an enhancer of purinergic muscle contractions. It is also a competitive inhibitor of serotonin and dopamine transport. It is an anti-convulsant and has anti-addictive properties against cocaine and heroin.

Safety & Documentation

Safety Information

Symbol 
GHS07  GHS07
Signal word 
Warning
Hazard statements 
Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
NH6730000
Protocols & Articles
Peer-Reviewed Papers
15

References

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