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L2037 Sigma-Aldrich

β-Lapachone

≥98% (TLC)

  • CAS Number 4707-32-8

  • Empirical Formula (Hill Notation) C15H14O3

  • Molecular Weight 242.27

  •  MDL number MFCD01712233

  •  PubChem Substance ID 24278512

  •  NACRES NA.77

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Properties

Related Categories Apoptosis and Cell Cycle, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Biochemicals and Reagents, Cancer Research,
Quality Level   100
biological source   synthetic (organic)
assay   ≥98% (TLC)
form   powder
SMILES string   CC1(C)CCC2=C(O1)c3ccccc3C(=O)C2=O
InChI   1S/C15H14O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6H,7-8H2,1-2H3
InChI key   QZPQTZZNNJUOLS-UHFFFAOYSA-N

Description

Biochem/physiol Actions

β-Lapachone is a naturally occurring quinone obtained from the bark of the lapacho tree (Tabebuia avellanedae) with cancer chemopreventive properties. Induces apoptosis in HL-60 and human prostate cancer cells.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

Legal Information

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Safety & Documentation

Safety Information

Personal Protective Equipment 
RIDADR 
NONH for all modes of transport
WGK Germany 
WGK 3
RTECS 
QL6127400
Flash Point(F) 
Not applicable
Flash Point(C) 
Not applicable

Documents

Certificate of Analysis (COA)

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Certificate of Origin (COO)

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Protocols & Articles
Peer-Reviewed Papers
15

References

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