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L6668 Sigma

Lercanidipine hydrochloride

≥98% (HPLC)

Synonym: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester 3,5-pyridinedicarboxylic acid hydrochloride

  • CAS Number 132866-11-6

  • Empirical Formula (Hill Notation) C36H41N3O6 · HCl

  • Molecular Weight 648.19

  •  MDL number MFCD07773089

  •  PubChem Substance ID 24724527

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Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecule Alphabetical Index, Bioactive Small Molecules, Calcium Channel Modulators, Cell Biology,
InChI Key   WMFYOYKPJLRMJI-UHFFFAOYSA-N
assay   ≥98% (HPLC)
form   powder
storage condition   desiccated
  protect from light
color   yellow
originator   Forest Labs
storage temp.   2-8°C

Description

Packaging

10, 50 mg in glass bottle

Biochem/physiol Actions

Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine.

Features and Benefits

This compound is also offered as part of Sigma′s Library of Pharmacologically Active Compounds (LOPAC®1280), a biologically annotated collection of high-quality, ready-to-screen compounds. Click here to learn more.

This compound was developed by Forest Labs. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Legal Information

LOPAC is a registered trademark of Sigma-Aldrich Co. LLC

Safety & Documentation

Safety Information

Symbol 
GHS06  GHS06
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2811 6.1 / PGIII
WGK Germany 
3

Documents

Certificate of Analysis

Certificate of Origin


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Protocols & Articles

Articles

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Peer-Reviewed Papers
15

References

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